Long-Term Relationships between Synaptic Tenacity, Synaptic Remodeling, and Network Activity
نویسندگان
چکیده
منابع مشابه
Long-Term Relationships between Synaptic Tenacity, Synaptic Remodeling, and Network Activity
Synaptic plasticity is widely believed to constitute a key mechanism for modifying functional properties of neuronal networks. This belief implicitly implies, however, that synapses, when not driven to change their characteristics by physiologically relevant stimuli, will maintain these characteristics over time. How tenacious are synapses over behaviorally relevant time scales? To begin to add...
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Synaptic plasticity - the directed modulation of synaptic connections by specific activity histories or physiological signals - is believed to be a major mechanism for the modification of neuronal network function. This belief, however, has a 'flip side': the supposition that synapses do not change spontaneously in manners unrelated to such signals. Contrary to this supposition, recent studies ...
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ژورنال
عنوان ژورنال: PLoS Biology
سال: 2009
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.1000136